Structure of PDB 5vz5 Chain A

Receptor sequence
>5vz5A (length=277) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAP
WIEQEGPEYWDRETQISKTNTQTYRESLRNLRGYYNQSEAGSHTLQRMYG
CDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
REAEQWRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEPS
3D structure
PDB5vz5 A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations.
ChainA
Resolution2.5901 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 Y9 M45 E63 S67 N70 T73 Y74 E76 S77 Y84 L95 R97 Y99 D114 S116 K146 W147 Q155 W156 Y159 W167 Y171 Y7 Y9 M45 E63 S67 N70 T73 Y74 E76 S77 Y84 L95 R97 Y99 D114 S116 K146 W147 Q155 W156 Y159 W167 Y171
External links
PDB RCSB:5vz5, PDBe:5vz5, PDBj:5vz5
PDBsum5vz5
PubMed29441070
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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