Structure of PDB 5vyu Chain A

Receptor sequence
>5vyuA (length=244) Species: 224914 (Brucella melitensis bv. 1 str. 16M) [Search protein sequence]
AIAPNTRVLVAGYGLPAEFCVTTLIGMGVEIDKIAVATHREDNRNCGLHS
MLRLRNIQFTTAAANSEEFYEFGANFAPDMIISMHYRSLIPGRFLKLAKK
GSVNLHPSLLPAYRGTNSVAWVIINGESETGFSYHRMDENADTGAILLQE
RISVEETDTAFSLFHRQIARAMLRLEEVILKLDQGDPGFAQLGEASYYAR
ELPFGGVIDPRWSEVQIDRFIRAMFFPPFPPAVLYYVPSIDIYR
3D structure
PDB5vyu Biochemical Characterization of WbkC, an N-Formyltransferase from Brucella melitensis.
ChainA
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N105 H107 S134 D143
Catalytic site (residue number reindexed from 1) N104 H106 S133 D142
Enzyme Commision number 2.1.2.14: GDP-perosamine N-formyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1YA A Y87 R88 S89 L90 I91 N105 M138 D139 E140 N141 A142 Y86 R87 S88 L89 I90 N104 M137 D138 E139 N140 A141
BS02 JB2 A R45 R88 T117 N118 F165 L203 F227 F230 R44 R87 T116 N117 F164 L202 F226 F229
Gene Ontology
Molecular Function
GO:0004479 methionyl-tRNA formyltransferase activity
GO:0008446 GDP-mannose 4,6-dehydratase activity
GO:0016740 transferase activity
Biological Process
GO:0006413 translational initiation
GO:0009058 biosynthetic process
GO:0009103 lipopolysaccharide biosynthetic process
GO:0071951 conversion of methionyl-tRNA to N-formyl-methionyl-tRNA
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:5vyu, PDBe:5vyu, PDBj:5vyu
PDBsum5vyu
PubMed28636341
UniProtF8WJP6|WBKC_BRUME GDP-perosamine N-formyltransferase (Gene Name=wbkC)

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