Structure of PDB 5vwz Chain A

Receptor sequence
>5vwzA (length=166) Species: 9606 (Homo sapiens) [Search protein sequence]
SMSEEQVAQDTEEVFRSYVFYRHQQEQEAEGVAAPADPEMVTLPLQPSST
MGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFE
SGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARW
IAQRGGWVAALNLGNG
3D structure
PDB5vwz Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.
ChainA
Resolution1.622 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R42 I81 G82 I85 N86 R88 Y89 E92 F93 M96 I114 S117 L118 S121 N124 G126 R127 V129 A130 F134 R137 G184 R22 I61 G62 I65 N66 R68 Y69 E72 F73 M76 I94 S97 L98 S101 N104 G106 R107 V109 A110 F114 R117 G164
BS02 peptide A G51 Q94 G31 Q74
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:5vwz, PDBe:5vwz, PDBj:5vwz
PDBsum5vwz
PubMed29149594
UniProtQ16611|BAK_HUMAN Bcl-2 homologous antagonist/killer (Gene Name=BAK1)

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