Structure of PDB 5vwy Chain A

Receptor sequence
>5vwyA (length=153) Species: 9606 (Homo sapiens) [Search protein sequence]
SEEQVAQDTEEVFRSYVFYRHQQEQEDPEMVTQPSSTMGQVGRQLAIIGD
DINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLG
FGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGWVAALNL
GNG
3D structure
PDB5vwy Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.
ChainA
Resolution1.555 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R42 I81 I85 R88 Y89 E92 F93 M96 I114 S117 L118 S121 N124 G126 R127 A130 G133 F134 R137 R20 I48 I52 R55 Y56 E59 F60 M63 I81 S84 L85 S88 N91 G93 R94 A97 G100 F101 R104
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:5vwy, PDBe:5vwy, PDBj:5vwy
PDBsum5vwy
PubMed29149594
UniProtQ16611|BAK_HUMAN Bcl-2 homologous antagonist/killer (Gene Name=BAK1)

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