Structure of PDB 5vwv Chain A

Receptor sequence
>5vwvA (length=170) Species: 9606 (Homo sapiens) [Search protein sequence]
GPLGSMSEEQVAQDTEEVFRSYVFYRHQQEQEAEGVAAPADPEMVTLPLQ
PSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIAT
SLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHS
IARWIAQRGGWVAALNLGNG
3D structure
PDB5vwv Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.
ChainA
Resolution1.897 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I81 Y89 E92 F93 M96 H99 L100 K113 I114 S117 L118 N124 G126 R127 A130 F134 I65 Y73 E76 F77 M80 H83 L84 K97 I98 S101 L102 N108 G110 R111 A114 F118
BS02 TFA A R42 N86 R137 R26 N70 R121
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:5vwv, PDBe:5vwv, PDBj:5vwv
PDBsum5vwv
PubMed29149594
UniProtQ16611|BAK_HUMAN Bcl-2 homologous antagonist/killer (Gene Name=BAK1)

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