Structure of PDB 5vvu Chain A

Receptor sequence
>5vvuA (length=424) Species: 9606 (Homo sapiens) [Search protein sequence]
HFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWR
EMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKL
DQVSQFGCRSFALLFDNIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGE
PETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKE
IPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLK
GVLTNPNCEFEANYVAIHTLATWYKYSPQMALKLALTEWLQEFGVPHQYS
VTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVIEEWRSRAAK
FEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGC
RSWAFRGGLAGEFQRLLPIDGAND
3D structure
PDB5vvu Structural insights into the substrate binding adaptability and specificity of human O-GlcNAcase.
ChainA
Resolution2.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.2.1.169: protein O-GlcNAcase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A N175 Y219 F223 N117 Y161 F165
BS02 peptide A F625 W645 F362 W382
External links
PDB RCSB:5vvu, PDBe:5vvu, PDBj:5vvu
PDBsum5vvu
PubMed28939839
UniProtO60502|OGA_HUMAN Protein O-GlcNAcase (Gene Name=OGA)

[Back to BioLiP]