Structure of PDB 5vrf Chain A

Receptor sequence
>5vrfA (length=282) Species: 211586 (Shewanella oneidensis MR-1) [Search protein sequence]
YDFWVKLASRASVATALTLITIKLLAWLYSGSASMLASLTDSFADTLASI
INFIAIRYAIVPADHDHRYGHGKAEPLAALAQSAFIMGSAFLLLFYGGER
LLNPSPVENATLGVVVSVVAIVLTLALVLLQKRALAATNSTVVEADSLHY
KSDLFLNAAVLLALVLSQYGWWWADGLFAVLIACYIGQQAFDLGYRSIQA
LLDRELDEDTRQRIKLIAKEDPRVLGLHDLRTRQAGKTVFIQFHLELDGN
LSLNEAHSITDTTGLRVKAAFEDAEVIIHQDP
3D structure
PDB5vrf Structural basis for the alternating access mechanism of the cation diffusion facilitator YiiP.
ChainA
Resolution4.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H285 D287 H279 D281
BS02 ZN A D47 D51 H155 D159 D41 D45 H149 D153
BS03 ZN A D70 H73 H77 D64 H67 H71
BS04 ZN A H234 H250 D287 H228 H244 D281
Gene Ontology
Molecular Function
GO:0008324 monoatomic cation transmembrane transporter activity
GO:0015086 cadmium ion transmembrane transporter activity
GO:0015093 ferrous iron transmembrane transporter activity
GO:0015341 zinc efflux active transmembrane transporter activity
GO:0046872 metal ion binding
Biological Process
GO:0006812 monoatomic cation transport
GO:0006826 iron ion transport
GO:0006829 zinc ion transport
GO:0006882 intracellular zinc ion homeostasis
GO:0034220 monoatomic ion transmembrane transport
GO:0034755 iron ion transmembrane transport
GO:0055085 transmembrane transport
GO:0070574 cadmium ion transmembrane transport
GO:0071577 zinc ion transmembrane transport
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:5vrf, PDBe:5vrf, PDBj:5vrf
PDBsum5vrf
PubMed29507252
UniProtQ8E919|FIEF_SHEON Cation-efflux pump FieF (Gene Name=fieF)

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