Structure of PDB 5vmf Chain A

Receptor sequence
>5vmfA (length=321) Species: 88776 (Influenza A virus (A/Brevig Mission/1/1918(H1N1))) [Search protein sequence]
DTICIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDSHNGKLCKLKGIAPL
QLGKCNIAGWLLGNPECDLLLTASSWSYIVETSNSENGTCYPGDFIDYEE
LREQLSSVSSFEKFEIFPKTSSWPNHETTGVTAACSYAGASSFYRNLLWL
TKKGSSYPKLSKSYVNNKGKEVLVLWGVHHPPTGTDQQSLYQNADAYVSV
GSSKYNRRFTPEIAARPKVRDLASRMNYYWTLLEPGDTITFEATGNLIAP
WYAFALNRGSGSGIITSDAPVHDCNTKCQTPHGAINSSLPFQNIHPVTIG
ECPKYVRSTKLRMATGLRNIP
3D structure
PDB5vmf Determinant of receptor-preference switch in influenza hemagglutinin.
ChainA
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GAL A K218 D221 K218 D221
BS02 SIA A Y91 V131 T132 A133 H179 S224 Y91 V131 T132 A133 H179 S224
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane
Cellular Component
GO:0019031 viral envelope

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5vmf, PDBe:5vmf, PDBj:5vmf
PDBsum5vmf
PubMed29055255
UniProtQ9WFX3|HEMA_I18A0 Hemagglutinin (Gene Name=HA)

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