Structure of PDB 5vk1 Chain A

Receptor sequence
>5vk1A (length=83) Species: 9606 (Homo sapiens) [Search protein sequence]
NQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDAAAQHMV
YCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLV
3D structure
PDB5vk1 Dithiocarbamate-inspired side chain stapling chemistry for peptide drug design.
ChainA
Resolution2.69 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K50 M53 G57 I60 Q71 V92 K26 M29 G33 I36 Q47 V68
BS02 peptide A V49 M53 Y99 V25 M29 Y75
Gene Ontology
Biological Process
GO:0043066 negative regulation of apoptotic process
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:5vk1, PDBe:5vk1, PDBj:5vk1
PDBsum5vk1
PubMed30809370
UniProtO15151|MDM4_HUMAN Protein Mdm4 (Gene Name=MDM4)

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