Structure of PDB 5vc8 Chain A

Receptor sequence
>5vc8A (length=125) Species: 9606 (Homo sapiens) [Search protein sequence]
HLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKARQYHVQFFGDA
PERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRA
QWEMGIVQAEEAASMSVEERKAKFT
3D structure
PDB5vc8 Histone and DNA binding ability studies of the NSD subfamily of PWWP domains.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.357: [histone H3]-lysine(36) N-dimethyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A K304 A305 K84 A85
External links
PDB RCSB:5vc8, PDBe:5vc8, PDBj:5vc8
PDBsum5vc8
PubMed34271259
UniProtO96028|NSD2_HUMAN Histone-lysine N-methyltransferase NSD2 (Gene Name=NSD2)

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