Structure of PDB 5vbq Chain A

Receptor sequence
>5vbqA (length=112) Species: 9606 (Homo sapiens) [Search protein sequence]
GAASTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPM
DLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEK
LFMQKLSQMPQE
3D structure
PDB5vbq Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors.
ChainA
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 R78 A P51 L61 Q62 L63 Y66 Y108 N109 I115 P27 L37 Q38 L39 Y42 Y84 N85 I91 BindingDB: IC50=1400nM
External links
PDB RCSB:5vbq, PDBe:5vbq, PDBj:5vbq
PDBsum5vbq
PubMed34710325
UniProtQ58F21|BRDT_HUMAN Bromodomain testis-specific protein (Gene Name=BRDT)

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