Structure of PDB 5vax Chain A

Receptor sequence
>5vaxA (length=143) Species: 9606 (Homo sapiens) [Search protein sequence]
YDNREIVMKYIHYKLSQRGYEWDTESEVVHLTLRQAGDDFSRRYRRDFAE
MSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNR
EMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMR
3D structure
PDB5vax Bcl-2 complex with Beclin 1 pT108 BH3 domain
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A A100 F104 R107 Y108 F112 M115 H120 R129 V133 E136 L137 D140 N143 G145 R146 Y202 A36 F40 R43 Y44 F48 M51 H56 R65 V69 E72 L73 D76 N79 G81 R82 Y138
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

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Biological Process
External links
PDB RCSB:5vax, PDBe:5vax, PDBj:5vax
PDBsum5vax
PubMed
UniProtP10415|BCL2_HUMAN Apoptosis regulator Bcl-2 (Gene Name=BCL2)

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