Structure of PDB 5vau Chain A

Receptor sequence
>5vauA (length=151) Species: 9606 (Homo sapiens) [Search protein sequence]
GSMAHAGRTGYDNREIVMKYIHYKLSQRGYEWDASEVVHLTLRQAGDDFS
RRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGG
VMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGPS
M
3D structure
PDB5vau Bcl-2 complex with Beclin 1 BH3 domain
ChainA
Resolution1.754 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A F104 R107 Y108 F112 M115 R129 E136 L137 D140 N143 G145 R146 F153 Y202 F49 R52 Y53 F57 M60 R74 E81 L82 D85 N88 G90 R91 F98 Y147
BS02 peptide A D111 F112 D56 F57
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:5vau, PDBe:5vau, PDBj:5vau
PDBsum5vau
PubMed
UniProtP10415|BCL2_HUMAN Apoptosis regulator Bcl-2 (Gene Name=BCL2)

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