Structure of PDB 5v6a Chain A

Receptor sequence
>5v6aA (length=320) Species: 1235996 (Human betacoronavirus 2c EMC/2012) [Search protein sequence]
QQLTIEVLVTVDGVNFRTVVLNNKNTYRSQLGCVFFNGADISDTIPDEKQ
NGHSLYLADNLTADETKALKELYGPVDPTFLHRFYSLKAAVHGWKMVVCD
KVRSLKLSDNNCYLNAVIMTLDLLKDIKFVIPALQHAFMKHKGGDSTDFI
ALIMAYGNCTFGAPDDASRLLHTVLAKAELCCSARMVWREWCNVCGIKDV
VLQGLKACCYVGVQTVEDLRARMTYVCQCGGERHRQLVEHTTPWLLLSGT
PNEKLVTTSTAPDFVAFNVFQGIETAVGHYVHARLKGGLILKFDSGTVSK
TSDWKCKVTDVLFPGQKYSS
3D structure
PDB5v6a Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.57: methyltransferase cap1.
3.4.19.12: ubiquitinyl hydrolase 1.
3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C1672 C1675 C1707 C192 C195 C227
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:5v6a, PDBe:5v6a, PDBj:5v6a
PDBsum5v6a
PubMed28542609
UniProtK0BWD0

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