Structure of PDB 5v3w Chain A

Receptor sequence
>5v3wA (length=277) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
QIDGFVRTLRARPEAGGKVPVFVFHPAGGSTVVYEPLLGRLPADTPMYGF
ERVEGSIEERAQQYVPKLIEMQGDGPYVLVGWSLGGVLAYACAIGLRRLG
KDVRFVGLIDAVRAGEEIPQTKEEIRKRWDRYAAFAEKTFNVTIPAIPYE
QLEELDDEGQVRFVLDAVSQSGVQIPAGIIEHQRTSYLDNRAIDTAQIQP
YDGHVTLYMADRYHDDAIMFEPRYAVRQPDGGWGEYVSDLEVVPIGGEHI
QAIDEPIIAKVGEHMSRALGQIEADRT
3D structure
PDB5v3w Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13.
ChainA
Resolution1.723 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 2Q5 A S1533 V1562 N1640 I1643 Y1663 Y1674 S83 V112 N190 I193 Y213 Y224
Gene Ontology
Biological Process
GO:0009058 biosynthetic process

View graph for
Biological Process
External links
PDB RCSB:5v3w, PDBe:5v3w, PDBj:5v3w
PDBsum5v3w
PubMed28669536
UniProtI6X8D2|PKS13_MYCTU Polyketide synthase Pks13 (Gene Name=pks13)

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