Structure of PDB 5v3r Chain A

Receptor sequence
>5v3rA (length=357) Species: 9606 (Homo sapiens) [Search protein sequence]
ATFISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRR
AAVGRPLDKHEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDK
GSLFGGSVKLALASLGYEKSCVLFNCAALASQIAAEQNLDNDEGLKIAAK
HYQFASGAFLHIKETVLSALSREPTVDISPDTVGTLSLIMLAQAQEVFFL
KATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPKEVFPVLAAKHCI
MQANAEYHQSILAKQQKKFGEEIARLQHAAELIKTVASRYDEYVNVKDFS
DKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTPVNVPISQKF
TDLFEKM
3D structure
PDB5v3r A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability.
ChainA
Resolution1.906 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A D143 K147 F199 K202 M208 I212 L337 D142 K146 F198 K201 M207 I211 L336
Gene Ontology
Biological Process
GO:0071985 multivesicular body sorting pathway

View graph for
Biological Process
External links
PDB RCSB:5v3r, PDBe:5v3r, PDBj:5v3r
PDBsum5v3r
PubMed30181294
UniProtQ8WUM4|PDC6I_HUMAN Programmed cell death 6-interacting protein (Gene Name=PDCD6IP)

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