Structure of PDB 5v35 Chain A

Receptor sequence
>5v35A (length=152) Species: 9606 (Homo sapiens) [Search protein sequence]
NVEGVKKTILHGGTGELPNFITGSRVIFHFRTMKCDEERTVIDDSRQVGQ
PMHIIIGNMFKLEFWEILLTSMRVHEVAEFWCDTIHTGVYPILSRSLRQM
AQGKDPTEWHVHTCGLANMFAYHTLGYEDLDELQKEPQPLVFVIELLQVD
AP
3D structure
PDB5v35 Unique structural features of the AIPL1-FKBP domain that support prenyl lipid binding and underlie protein malfunction in blindness.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAR A F37 M59 I61 L100 F149 F30 M52 I54 L93 F142 PDBbind-CN: -logKd/Ki=6.96,Kd=110nM
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity

View graph for
Molecular Function
External links
PDB RCSB:5v35, PDBe:5v35, PDBj:5v35
PDBsum5v35
PubMed28739921
UniProtQ9NZN9|AIPL1_HUMAN Aryl-hydrocarbon-interacting protein-like 1 (Gene Name=AIPL1)

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