Structure of PDB 5v1m Chain A

Receptor sequence
>5v1mA (length=185) Species: 9606 (Homo sapiens) [Search protein sequence]
MGNWATHVYVPYEAKEEFLDLLDVLLPHAQTYVPRLVRMKVFHLSLSQSV
VLRHHWILPFVQALKARMTSFHRFFFTANQVKIYTNQEKTRTFIGLEVTS
GHAQFLDLVSEVDRVMEEFNLTTFYQDPSFHLSLAWCVGDARLQLEGQCL
QELQAIVDGFEVLLRVHTEQVRCKSGNKFFSMPLK
3D structure
PDB5v1m Usb1 controls U6 snRNP assembly through evolutionarily divergent cyclic phosphodiesterase activities.
ChainA
Resolution1.47 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.6.1.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 U5P A H120 S122 Y202 P205 S206 H208 H43 S45 Y125 P128 S129 H131
Gene Ontology
Molecular Function
GO:0004518 nuclease activity
Biological Process
GO:0034477 U6 snRNA 3'-end processing

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Molecular Function

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Biological Process
External links
PDB RCSB:5v1m, PDBe:5v1m, PDBj:5v1m
PDBsum5v1m
PubMed28887445
UniProtQ9BQ65|USB1_HUMAN U6 snRNA phosphodiesterase 1 (Gene Name=USB1)

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