Structure of PDB 5v0u Chain A

Receptor sequence
>5v0uA (length=407) Species: 381518 (Influenza A virus (A/Wilson-Smith/1933(H1N1))) [Search protein sequence]
RPLRLPDGPPCSQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMRTFF
GWKEPNVVKPHEKGINPNYLLSWKQVLAELQDIENEEKIPRTKNMKKTSQ
LKWALGEELRSLASWIQNEFNKACELTDSSWIELDEIGEDAAPIEHIASM
RRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRT
KEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYC
VLEVGDMLLRSAIGHVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQ
IESMIEAESSVKEKDMTKEFFENKSPKGVEEGSIGKVCRTLLAKSVFNSL
YASPQLEGFSAESRKLLLIVQALRDNLGGLYEAIEECLINDPWVLLNASW
FNSFLTH
3D structure
PDB5v0u Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase
ChainA
Resolution2.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 8QG A R312 W317 L342 R47 W52 L77
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

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Molecular Function

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Biological Process
External links
PDB RCSB:5v0u, PDBe:5v0u, PDBj:5v0u
PDBsum5v0u
PubMed
UniProtP15659|PA_I33A0 Polymerase acidic protein (Gene Name=PA)

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