Structure of PDB 5uwx Chain A

Receptor sequence
>5uwxA (length=346) Species: 1502 (Clostridium perfringens) [Search protein sequence]
SNAMARILKTAYTFDDVLLVPNKSEVLPNEVSLKTQLTKKIQLNIPLMSA
SMDTVTESKMAIAMAREGGIGIIHKNMTIEDQAREVDRVKRSGGLLCGAS
IGVTNDMMERVDAVVKAKVDVIVLDTAHGHSKGVIEGVKRIKAKYPELQV
IAGNIATPEAVRDLAEAGADCVKVGIGPGSICTTRIVAGVGVPQLTAVMD
CAEEGKKLGIPVIADGGLKYSGDIVKALAAGACAAMMGSIFAGCEEAPGA
IEIYQGRSYKVYRGMGSLGAMAFVPEGVEGRIAYKGHLADTIYQLIGGIK
SGMGYLGAPTLENLYENANFVVQTSAGFRESHPHDINITKEAPNYS
3D structure
PDB5uwx Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P176
ChainA
Resolution1.85 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.1.1.205: IMP dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8L7 A V224 A248 S252 G254 M386 G387 M392 E411 V103 A127 S131 G133 M265 G266 M271 E276
BS02 IMP A M49 G300 S301 I302 C303 D336 G338 M358 G359 S360 Y383 G385 M386 G387 E411 M52 G179 S180 I181 C182 D215 G217 M237 G238 S239 Y262 G264 M265 G266 E276
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0003938 IMP dehydrogenase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006164 purine nucleotide biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5uwx, PDBe:5uwx, PDBj:5uwx
PDBsum5uwx
PubMed
UniProtA0A127ELD1

[Back to BioLiP]