Structure of PDB 5uvz Chain A

Receptor sequence
>5uvzA (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
SHMEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPM
DMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQD
VFEMRFAKM
3D structure
PDB5uvz BRD4 Bromodomain 2 with A-1354689
ChainA
Resolution1.63 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8NP A W374 P375 F376 N433 H437 M442 W26 P27 F28 N85 H89 M94 BindingDB: Ki=1700nM,EC50=2300nM
External links
PDB RCSB:5uvz, PDBe:5uvz, PDBj:5uvz
PDBsum5uvz
PubMed
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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