Structure of PDB 5uvu Chain A

Receptor sequence
>5uvuA (length=107) Species: 9606 (Homo sapiens) [Search protein sequence]
MEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDM
STIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVF
EMRFAKM
3D structure
PDB5uvu Complex structure of BRD4_BD2_A-1461028
ChainA
Resolution1.66 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8O4 A W374 P375 V380 L385 N433 W24 P25 V30 L35 N83 BindingDB: Ki=8.4nM,IC50=4.6nM
External links
PDB RCSB:5uvu, PDBe:5uvu, PDBj:5uvu
PDBsum5uvu
PubMed
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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