Structure of PDB 5uv2 Chain A

Receptor sequence
>5uv2A (length=514) Species: 2711 (Citrus sinensis) [Search protein sequence]
SIWDHDFLQSLNSNYTDETYKRRAEELKGKVKTAIKDVTEPLDQLELIDN
LQRLGLAYHFEPEIRNILRNIHNHNKDYNWRKENLYATSLEFRLLRQHGY
PVSQEVFSGFKDDKVGFICDDFKGILSLHEASYYSLEGESIMEEAWQFTS
KHLKEMMIDVFVAEQAKRALELPLHWKAPMLEARWFIHVYEKREDKNHLL
LELAKLEFNTLQAIYQEELKDISGWWKDTGLGEKLSFARNRLVASFLWSM
GIAFEPQFAYCRRVLTISIALITVIDDIYDVYGTLDELEIFTDAVARWDI
NYALKHLPGYMKMCFLALYNFVNEFAYYVLKQQDFDMLLSIKHAWLGLIQ
AYLVEAKWYHSKYTPKLEEYLENGLVSITGPLIITISYLSGTNPIIKKEL
EFLESNPDIVHWSSKIFRLQDDLGTSSDEIQRGDVPKSIQCYMHETGASE
EVAREHIKDMMRQMWKKVNAYTADKDSPLTRTTAEFLLNLVRMSHFMYLH
GDVGFTLLFQPIPL
3D structure
PDB5uv2 Structural Characterization of Early Michaelis Complexes in the Reaction Catalyzed by (+)-Limonene Synthase from Citrus sinensis Using Fluorinated Substrate Analogues.
ChainA
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) R306 W315 I336 D343 D347 S444 I445 T446 R485 D488 T492 E496 Y565
Catalytic site (residue number reindexed from 1) R239 W248 I269 D276 D280 S377 I378 T379 R418 D421 T425 E429 Y498
Enzyme Commision number 4.2.3.20: (R)-limonene synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D343 D347 D276 D280
BS02 MN A D343 D347 D276 D280
BS03 LA6 A W315 I336 T340 D343 I445 F484 R485 D488 K504 W248 I269 T273 D276 I378 F417 R418 D421 K437 MOAD: Ki=39.5uM
PDBbind-CN: -logKd/Ki=4.40,Ki=39.5uM
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0010333 terpene synthase activity
GO:0016829 lyase activity
GO:0034002 (R)-limonene synthase activity
GO:0046872 metal ion binding
Biological Process
GO:0016102 diterpenoid biosynthetic process
Cellular Component
GO:0009507 chloroplast

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5uv2, PDBe:5uv2, PDBj:5uv2
PDBsum5uv2
PubMed28272876
UniProtA0A1C9J6A7|RLC1_CITSI (R)-limonene synthase 1, chloroplastic

[Back to BioLiP]