Structure of PDB 5upy Chain A

Receptor sequence
>5upyA (length=350) Species: 169963 (Listeria monocytogenes EGD-e) [Search protein sequence]
NAMWETKFAKEGLTFDDVLLVPAKSDVLPNDVDLSVEMAPSLKLNVPIWS
AGMDTITEAKMAIAIARQGGIGVVHKNMSIEQQAEEIEKVKRSGGLLAAA
AVGITNDTFVRVEKLIEAGVDAIVIDTAHGHSAGVINKISEIRQTFKDVV
IVAGNVATAEGARALFEVGVDIVKVGIGPGSICTTRVVAGVGVPQITAIY
DCATVAREFGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMLAGTDESPG
ETEIFQGRQFKTYRGMGSLAAMEHGKLVPEGIEGRVPYKGSVADIIFQLV
GGIRSGMGYTGSPDLRHLREEAAFVRMTGAGLRESHPHDIQITKEAPNYS
3D structure
PDB5upy Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Listeria Monocytogenes in the complex with IMP and Q21
ChainA
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.205: IMP dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IMP A M51 G305 S306 I307 C308 D341 G343 G364 S365 Y388 G390 M391 G392 E416 M53 G180 S181 I182 C183 D216 G218 G239 S240 Y263 G265 M266 G267 E280
BS02 Q21 A A253 S257 M391 G392 L413 E416 A128 S132 M266 G267 L277 E280
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0003938 IMP dehydrogenase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006164 purine nucleotide biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5upy, PDBe:5upy, PDBj:5upy
PDBsum5upy
PubMed
UniProtQ926Y9

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