Structure of PDB 5un1 Chain A

Receptor sequence
>5un1A (length=416) Species: 8355 (Xenopus laevis) [Search protein sequence]
TRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPDETIPG
RPTVPQCCYGFCVDLLIKLAREMDFTYEVHLVADGKFGTQERVNNSNAAA
WNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIP
RSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFLTLSSAMWFSWRVL
LNSGLGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLRRPEERITG
INDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAE
AIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDS
PWKQEVSLNILKSHENGFMEELDKTWVRYQECDSPATLTFENMAGVFMLV
AGGIVAGIFLIFIEIA
3D structure
PDB5un1 Mechanism of NMDA receptor channel block by MK-801 and memantine.
ChainA
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLY A F482 P514 L515 T516 R521 S677 S678 F87 P119 L120 T121 R126 S271 S272
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0015276 ligand-gated monoatomic ion channel activity
GO:0038023 signaling receptor activity
Biological Process
GO:0006811 monoatomic ion transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5un1, PDBe:5un1, PDBj:5un1
PDBsum5un1
PubMed29670280
UniProtA0A1L8F5J9|NMDZ1_XENLA Glutamate receptor ionotropic, NMDA 1 (Gene Name=grin1)

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