Structure of PDB 5uml Chain A

Receptor sequence
>5umlA (length=84) Species: 9606 (Homo sapiens) [Search protein sequence]
NQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDAAAQHMV
YCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVT
3D structure
PDB5uml Design of ultrahigh-affinity and dual-specificity peptide antagonists of MDM2 and MDMX for p53 activation
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A M53 G57 I60 M61 Q71 H72 V92 K93 M29 G33 I36 M37 Q47 H48 V68 K69
Gene Ontology
Biological Process
GO:0043066 negative regulation of apoptotic process
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:5uml, PDBe:5uml, PDBj:5uml
PDBsum5uml
PubMed
UniProtO15151|MDM4_HUMAN Protein Mdm4 (Gene Name=MDM4)

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