Structure of PDB 5ulu Chain A

Receptor sequence

>5uluA (length=320) Species: 10090 (Mus musculus) [Search protein sequence]

PLFTEGTYQAEVMENSPAGTPLTVLNGPILALVTYQLLGTHSDLFVIDNS
TGVVTVRSGIIIDREAFSPPFLELLLLAEDIGQLNGTAHLFITILDDNDN
WPTFSPPTYTVHLLENCPPGFPVLQVTATDEDSGLNGELVYRIEAGAQDR
FLIHPVTGVIRVGNATIDREEQESYRLTVVATNRGTVPLSGTAIVTILID
DINDSRPEFLNPIQTVSVLESAEPGTIIANVTAIDLDLNPKLEYHIISIV
AKDDTDRLVPDQEDAFAVNINTGSVMVKSPLNRELVATYEVTLSVIDNAS
DLPEHSVSVPNAKLTVNILD

3D structure

PDB

5ulu Zooming in on Cadherin-23: Structural Diversity and Potential Mechanisms of Inherited Deafness.

Chain

Resolution

2.85 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	CA	A	E1947 D2005 E2007 D2041	E14 D63 E65 D99
BS02	CA	A	E1947 E2007 D2038 D2039 D2041 D2074	E14 E65 D96 D97 D99 D132
BS03	CA	A	N2040 N2042 D2072 D2074 N2078 N2125	N98 N100 D130 D132 N136 N183
BS04	CA	A	E2057 D2110 E2112 D2146	E115 D168 E170 D204
BS05	CA	A	E2057 E2112 D2143 I2144 D2146 D2179	E115 E170 D201 I202 D204 D237
BS06	CA	A	N2145 S2147 D2177 D2179 D2239	N203 S205 D235 D237 D297

Gene Ontology

	Molecular Function
GO:0005509	calcium ion binding

	Biological Process
GO:0007155	cell adhesion
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609	cell-cell adhesion

	Cellular Component
GO:0005886	plasma membrane
GO:0016020	membrane

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:5ulu, PDBe:5ulu, PDBj:5ulu
PDBsum	5ulu
PubMed	30033219
UniProt	Q99PF4\|CAD23_MOUSE Cadherin-23 (Gene Name=Cdh23)

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