Structure of PDB 5ujc Chain A

Receptor sequence
>5ujcA (length=267) Species: 6239 (Caenorhabditis elegans) [Search protein sequence]
EMSHAESIKRVVDQKLSSHEGFESHMFKIGSYNEAVGESSPFALPYDDST
MALLILSTPDMFDVAFRKWVVQKTMDFGSFDEVCEMVSSPIQSFLEDRLE
IMSEKLRKVEENFEILHDYSMTPQRRPKILMQTCGHVAGAAFYYQPCHFQ
EDGVTWPPAGRMGPNLKFIGLSLHPIYGGHFAFRSVLIFPNVKIPEFCEK
EPRPILTASEDVRTALEKFNYNWKDSGFRDFGNPTRRYSTTQMEFFGRPV
AERWEVLRPWVENLYFQ
3D structure
PDB5ujc Coordination chemistry controls the thiol oxidase activity of the B12-trafficking protein CblC.
ChainA
Resolution1.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.16.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COB A A38 V39 F45 D121 I132 L133 M134 Q135 T136 H139 Y146 Q148 L169 K170 I172 L174 S175 F186 F222 N223 W226 A35 V36 F42 D118 I129 L130 M131 Q132 T133 H136 Y143 Q145 L166 K167 I169 L171 S172 F183 F219 N220 W223
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0031419 cobalamin binding
GO:0032451 demethylase activity
GO:0033787 cyanocobalamin reductase (cyanide-eliminating) (NADP+) activity
GO:0043295 glutathione binding
GO:0071949 FAD binding
Biological Process
GO:0006749 glutathione metabolic process
GO:0009235 cobalamin metabolic process
GO:0070988 demethylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5ujc, PDBe:5ujc, PDBj:5ujc
PDBsum5ujc
PubMed28442570
UniProtQ7Z144|MMAC_CAEEL MMACHC-like protein (Gene Name=cblc-1)

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