Structure of PDB 5uj7 Chain A

Receptor sequence
>5uj7A (length=337) Species: 9606 (Homo sapiens) [Search protein sequence]
EARLRLHVSAVPESLPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTG
KTATVHEVIRCLQQAAQANDVPPFQYIEVNGMKLTEPHQVYVQILQKLTG
QKATANHAAELLAKQFCTTVLLVDELDLLWTHKQDIMYNLFDWPTHKEAR
LVVLAIANTMDLPERTRMCFQPYTYSQLQQILRSRLKHLKIQLVARKVAA
LSGDARRCLDICRRATEICEFVTIAHSMEAVDEMFSSSYITAIKNSSVLE
QSFLRAILAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCS
HLGSCRLLLVEPSRNDLLLRVRLNVSQDDVLYALKDE
3D structure
PDB5uj7 Structure of the active form of human Origin Recognition Complex and its ATPase motor module.
ChainA
Resolution3.394 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ATP A P536 G539 K540 T541 A542 E621 Y681 I689 P47 G50 K51 T52 A53 E125 Y173 I181
BS02 MG A T541 D620 T52 D124
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:5uj7, PDBe:5uj7, PDBj:5uj7
PDBsum5uj7
PubMed28112645
UniProtQ13415|ORC1_HUMAN Origin recognition complex subunit 1 (Gene Name=ORC1)

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