Structure of PDB 5ug7 Chain A

Receptor sequence
>5ug7A (length=126) Species: 10090 (Mus musculus) [Search protein sequence]
QRGLAHLVVSNFRAEHLAGDADTATDAYLKVFFGGQEFRTGVVWNNNNPR
WTDKMDFENVLLSTGGPLRVQVWDADAGADDDLLGSCDRSPHSGFHEVTC
ELNHGRVKFSYHAKCLPHLTGGTCLE
3D structure
PDB5ug7 Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A D429 T432 A433 D435 N454 D20 T23 A24 D26 N45
BS02 CA A D429 D435 D483 A484 D485 D20 D26 D74 A75 D76
BS03 CA A G428 D429 D483 D485 D491 G19 D20 D74 D76 D82
External links
PDB RCSB:5ug7, PDBe:5ug7, PDBj:5ug7
PDBsum5ug7
PubMed29416110
UniProtP10820|PERF_MOUSE Perforin-1 (Gene Name=Prf1)

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