Structure of PDB 5uet Chain A

Receptor sequence
>5uetA (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
SHMEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPM
DMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQD
VFEMRFAKM
3D structure
PDB5uet Complex structure of BRD4_BD2_A-1308586
ChainA
Resolution2.29 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 87V A W374 P375 F376 V380 N433 W26 P27 F28 V32 N85 BindingDB: Ki=12000nM
External links
PDB RCSB:5uet, PDBe:5uet, PDBj:5uet
PDBsum5uet
PubMed
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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