Structure of PDB 5ues Chain A

Receptor sequence
>5uesA (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
SHMEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPM
DMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQD
VFEMRFAKM
3D structure
PDB5ues Complex structure of BRD4_BD2_A-1344772
ChainA
Resolution1.62 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 87S A W374 P375 V380 N433 E438 W26 P27 V32 N85 E90 BindingDB: EC50=280nM,Ki=410nM
External links
PDB RCSB:5ues, PDBe:5ues, PDBj:5ues
PDBsum5ues
PubMed
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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