Structure of PDB 5uer Chain A

Receptor sequence
>5uerA (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
SHMEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPM
DMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQD
VFEMRFAKM
3D structure
PDB5uer Complex structure of BRD4_BD2_A-1359930
ChainA
Resolution1.87 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 87P A W374 P375 F376 K378 P379 V380 D381 L385 N433 H437 E438 M442 W26 P27 F28 K30 P31 V32 D33 L37 N85 H89 E90 M94 BindingDB: Ki=43.0nM,EC50=51nM
External links
PDB RCSB:5uer, PDBe:5uer, PDBj:5uer
PDBsum5uer
PubMed
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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