Structure of PDB 5ueq Chain A

Receptor sequence
>5ueqA (length=107) Species: 9606 (Homo sapiens) [Search protein sequence]
MEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDM
STIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVF
EMRFAKM
3D structure
PDB5ueq Complex structure of BRD4_BD2_A-1390146
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 87M A W374 P375 F376 V380 D381 L385 N433 H437 V439 M442 W24 P25 F26 V30 D31 L35 N83 H87 V89 M92 BindingDB: Ki=10nM,EC50=75nM
External links
PDB RCSB:5ueq, PDBe:5ueq, PDBj:5ueq
PDBsum5ueq
PubMed
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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