Structure of PDB 5uep Chain A

Receptor sequence
>5uepA (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
SHMEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPM
DMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQD
VFEMRFAKM
3D structure
PDB5uep Complex structure of BRD4_BD2_A-581577
ChainA
Resolution1.77 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 88P A P375 F376 V380 N433 P27 F28 V32 N85 BindingDB: Ki=25000nM
External links
PDB RCSB:5uep, PDBe:5uep, PDBj:5uep
PDBsum5uep
PubMed
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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