Structure of PDB 5ueo Chain A

Receptor sequence
>5ueoA (length=108) Species: 9606 (Homo sapiens) [Search protein sequence]
HMEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMD
MSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDV
FEMRFAKM
3D structure
PDB5ueo Complex structure of BRD4_BD2_A-1395017
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 87G A W374 P375 K378 P379 V380 D381 L385 N433 H437 E438 M442 W25 P26 K29 P30 V31 D32 L36 N84 H88 E89 M93 BindingDB: EC50=56nM,Ki=11nM
External links
PDB RCSB:5ueo, PDBe:5ueo, PDBj:5ueo
PDBsum5ueo
PubMed
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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