Structure of PDB 5ubg Chain A

Receptor sequence
>5ubgA (length=222) Species: 195099 (Campylobacter jejuni RM1221) [Search protein sequence]
NTRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRV
RDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGY
CRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTG
SVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALS
KEKQALVDKIMLRVAGVMQARE
3D structure
PDB5ubg A dimeric catalytic core relates the short and long forms of ATP-phosphoribosyltransferase.
ChainA
Resolution1.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.4.2.17: ATP phosphoribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H33 H35 H30 H32
BS02 PRT A Q12 G15 R16 R54 D55 N75 C104 L170 S172 S173 G174 A175 T176 Q9 G12 R13 R51 D52 N72 C101 L167 S169 S170 G171 A172 T173 PDBbind-CN: -logKd/Ki=5.17,IC50=6.8uM
BS03 ZN A D55 D56 D52 D53
Gene Ontology
Molecular Function
GO:0003879 ATP phosphoribosyltransferase activity
Biological Process
GO:0000105 L-histidine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5ubg, PDBe:5ubg, PDBj:5ubg
PDBsum5ubg
PubMed29208762
UniProtQ5HSJ4|HIS1_CAMJR ATP phosphoribosyltransferase (Gene Name=hisG)

[Back to BioLiP]