Structure of PDB 5u8c Chain A

Receptor sequence
>5u8cA (length=284) Species: 10116 (Rattus norvegicus) [Search protein sequence]
MSTRLKIVTIHQEPFVYVKPTMSDGTCKEEFTVNGDPVKKVICTGPNDRH
TVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWN
GMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKGTRIT
GINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAA
EAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKD
SPWKQNVSLSILKSHENGFMEDLDKTWVRYQECD
3D structure
PDB5u8c Novel Mode of Antagonist Binding in NMDA Receptors Revealed by the Crystal Structure of the GluN1-GluN2A Ligand-Binding Domain Complexed to NVP-AAM077.
ChainA
Resolution1.598 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLY A F92 P124 L125 T126 R131 S179 S180 D224 F85 P117 L118 T119 R124 S172 S173 D217
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:5u8c, PDBe:5u8c, PDBj:5u8c
PDBsum5u8c
PubMed28468946
UniProtP35439|NMDZ1_RAT Glutamate receptor ionotropic, NMDA 1 (Gene Name=Grin1)

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