Structure of PDB 5u7f Chain A

Receptor sequence
>5u7fA (length=144) Species: 83334 (Escherichia coli O157:H7) [Search protein sequence]
VYKRPVSILVVIYAQDTKRVLMLQRRDDPDFWQSVTGSVEEGETAPQAAM
REVKEEVTIDVVAEQLTLIDCQRTVEFEIFSHLRHRYAPGVTRNTESWFC
LALPHERQIVFTEHLAYKWLDAPAAAALTKSWSNRQAIEQFVIN
3D structure
PDB5u7f Metal ion coordination in the E. coli Nudix hydrolase dihydroneopterin triphosphate pyrophosphatase: New clues into catalytic mechanism.
ChainA
Resolution1.789 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.1.67: dihydroneopterin triphosphate diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SO4 A E82 R97 W136 E78 R93 W132
BS02 SO4 A K7 G41 E56 E117 K3 G37 E52 E113
BS03 CO A E56 E60 E117 E52 E56 E113
BS04 CO A T40 G41 E60 E117 T36 G37 E56 E113
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0008828 dATP diphosphatase activity
GO:0016787 hydrolase activity
GO:0019177 dihydroneopterin triphosphate pyrophosphohydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0046654 tetrahydrofolate biosynthetic process
GO:0046656 folic acid biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5u7f, PDBe:5u7f, PDBj:5u7f
PDBsum5u7f
PubMed28742822
UniProtP0AFC0|NUDB_ECOLI Dihydroneopterin triphosphate diphosphatase (Gene Name=nudB)

[Back to BioLiP]