Structure of PDB 5u3u Chain A

Receptor sequence
>5u3uA (length=255) Species: 9606 (Homo sapiens) [Search protein sequence]
VADLKAFSKHIYNAYLKNFNMTKKKARSILTAPFVIHDIETLWQAEKVWG
LPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKY
GVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEF
AVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFH
LQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQ
EIYKD
3D structure
PDB5u3u Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 7TV A L219 W228 V245 C249 T252 T253 H287 I290 L303 V305 I328 K331 H413 M417 L433 Y437 L42 W49 V61 C65 T68 T69 H103 I106 L119 V121 I144 K147 H229 M233 L249 Y253
BS02 B7G A L282 K283 E435 K438 L98 K99 E251 K254
BS03 B7G A N276 V279 N92 V95
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Cellular Component
External links
PDB RCSB:5u3u, PDBe:5u3u, PDBj:5u3u
PDBsum5u3u
PubMed28320959
UniProtQ03181|PPARD_HUMAN Peroxisome proliferator-activated receptor delta (Gene Name=PPARD)

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