Structure of PDB 5u32 Chain A

Receptor sequence
>5u32A (length=213) Species: 237561 (Candida albicans SC5314) [Search protein sequence]
LSTTTKYIFVPIATIGCGKTTVFNTLNNLFPQWTHIQNDNISKKAKLKIC
DLTLLALEDDDQSVVLFDRNNSASRERRQIFTTIDQKRDEHLDDTVDLKY
IAINFIPEDLSEEELWDITYNRVIQLDENLVESVMKGFIQRYQPINTSRS
PDDQFDHVIHLKLSKDENSSKSSLENVRIIIDDLVQNFPDLIKEKPADEL
INECFQKALDYKP
3D structure
PDB5u32 Structural basis for the GTP specificity of the RNA kinase domain of fungal tRNA ligase.
ChainA
Resolution2.191 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.5.1.3: RNA ligase (ATP).
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GDP A G422 G424 K425 T426 T427 R528 D583 K588 S589 S590 G16 G18 K19 T20 T21 R122 D166 K171 S172 S173
Gene Ontology
Molecular Function
GO:0003972 RNA ligase (ATP) activity
GO:0005524 ATP binding
Biological Process
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation

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Molecular Function

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Biological Process
External links
PDB RCSB:5u32, PDBe:5u32, PDBj:5u32
PDBsum5u32
PubMed29165709
UniProtP43075|TRNL_CANAL tRNA ligase (Gene Name=LIG1)

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