Structure of PDB 5tzg Chain A

Receptor sequence
>5tzgA (length=75) Species: 953739 (Streptomyces venezuelae ATCC 10712) [Search protein sequence]
KLVLDLERLAHVPQEKAGPLQRYAATIQSQRGAYNGKVLSIRQDDLRTLA
VIYDQSPSVLTEQLISWGVLDADAR
3D structure
PDB5tzg The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 C2E A R114 S123 R125 Q126 R31 S40 R42 Q43 PDBbind-CN: -logKd/Ki=5.80,Kd=1.6uM
BS02 C2E A I110 Q113 R114 R125 D128 I27 Q30 R31 R42 D45 PDBbind-CN: -logKd/Ki=5.80,Kd=1.6uM
Gene Ontology
Biological Process
GO:0045892 negative regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:5tzg, PDBe:5tzg, PDBj:5tzg
PDBsum5tzg
PubMed28449057
UniProtF2RCL8

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