Structure of PDB 5tyq Chain A

Receptor sequence
>5tyqA (length=306) Species: 1877 (Micromonospora echinospora) [Search protein sequence]
IVGGSTIQPERVDAAALRQLGDAMRKVVGSADPTPLADLLSGTPVDPDEL
TREVGADGRQALLDSGMAVDDGTTFSSPLRGHQLHGVVVLSDPDVEEEVQ
HRWYVDPLWEADLLIRLMLRRGGARALDMGCGSGVLSLVLADRYESVLGV
DVNPRAVALSRLNAALNGLTNVTFREGDMFEPAEGRFSRIVFNSPTNEEG
NEFVDLLEAGEPILETFFRNVPRKLESGGIVEVNLAMNDYPGDPFRERLA
DWLGLTENGLRVQIFTSQRRATESGGEWKRGWLVVAPGPVGLTEVEWPYH
DRYEED
3D structure
PDB5tyq Structural Basis of the Selectivity of GenN, an Aminoglycoside N-Methyltransferase Involved in Gentamicin Biosynthesis.
ChainA
Resolution2.163 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A D107 G131 C132 G133 V136 D152 V153 M180 N194 L207 I214 D106 G130 C131 G132 V135 D151 V152 M179 N193 L206 I213
BS02 MG A E98 D206 E97 D205
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0008168 methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:5tyq, PDBe:5tyq, PDBj:5tyq
PDBsum5tyq
PubMed28876898
UniProtQ2MG72

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