Structure of PDB 5tyi Chain A

Receptor sequence
>5tyiA (length=104) Species: 9606 (Homo sapiens) [Search protein sequence]
IHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHL
QKVKHYLILPSEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRH
CCTR
3D structure
PDB5tyi Discovery, Development, and Cellular Delivery of Potent and Selective Bicyclic Peptide Inhibitors of Grb7 Cancer Target.
ChainA
Resolution2.15 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R438 S460 R462 V468 K478 H479 Y480 L481 M495 D497 R14 S36 R38 V44 K54 H55 Y56 L57 M70 D72
External links
PDB RCSB:5tyi, PDBe:5tyi, PDBj:5tyi
PDBsum5tyi
PubMed29083893
UniProtQ14451|GRB7_HUMAN Growth factor receptor-bound protein 7 (Gene Name=GRB7)

[Back to BioLiP]