Structure of PDB 5txs Chain A

Receptor sequence
>5txsA (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAP
WIEQEGPEYWDRETQISKTNTQTYRESLRNLRGYYNQSEAGSHTLQRMYG
CDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
REAEQWRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB5txs A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations.
ChainA
Resolution1.697 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 Y9 M45 R62 E63 T69 N70 T73 E76 S77 Y84 R97 Y99 S116 K146 W147 E152 Q155 W156 Y159 W167 Y171 Y7 Y9 M45 R62 E63 T69 N70 T73 E76 S77 Y84 R97 Y99 S116 K146 W147 E152 Q155 W156 Y159 W167 Y171
External links
PDB RCSB:5txs, PDBe:5txs, PDBj:5txs
PDBsum5txs
PubMed29441070
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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