Structure of PDB 5tx9 Chain A

Receptor sequence
>5tx9A (length=358) Species: 93062 (Staphylococcus aureus subsp. aureus COL) [Search protein sequence]
TNSDVTPVQAANQYGYAGLSAAYEPTSAVNVSQTGQLLYQYNIDTKWNPA
SMTKLMTMYLTLEAVNKGQLSLDDTVTMTNKEYIMSTLPELSNTKLYPGQ
VWTIADLLQITVSNSSNAAALILAKKVSKNTSDFVDLMNNKAKAIGMKNT
HFVNPTGAANSRLRTFAPTKYKDQERTVTTARDYAILDLHVIKETPKILD
FTKQLAPTTHAVTYYTRNFSLEGAKMSLPGTDGLKTGSSDTANYNHTITT
KRGKFRINQVIMGAGDYKNLGGEKQRNMMGNALMERSFDQYKYVKILSKG
EQRINGKKYYVENDLYDVLPSDFSKKDYKLVVEDGKVHADYPREFINKDY
GPPTVEVH
3D structure
PDB5tx9 Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus.
ChainA
Resolution1.68 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A E336 H382 E312 H358
BS02 RB6 A A74 S75 L115 S139 R186 G261 S262 D264 Y268 Y291 A50 S51 L91 S115 R162 G237 S238 D240 Y244 Y267
Gene Ontology
Molecular Function
GO:0004180 carboxypeptidase activity
GO:0008800 beta-lactamase activity
GO:0009002 serine-type D-Ala-D-Ala carboxypeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0030655 beta-lactam antibiotic catabolic process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:5tx9, PDBe:5tx9, PDBj:5tx9
PDBsum5tx9
PubMed30366985
UniProtA0A0H2WY27

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