Structure of PDB 5tx6 Chain A

Receptor sequence
>5tx6A (length=88) Species: 10090 (Mus musculus) [Search protein sequence]
ALDAAYCFRNVQDNCCLRPLYIDFRKDLGWKWIHEPKGYNANFCAGACPK
SPSCVSQDLEPLTIVYYVGRKPKVEQLSNMIVKSCKCS
3D structure
PDB5tx6 An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling.
ChainA
Resolution2.746 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E99 Q100 E75 Q76
Gene Ontology
Molecular Function
GO:0008083 growth factor activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:5tx6, PDBe:5tx6, PDBj:5tx6
PDBsum5tx6
PubMed28228478
UniProtP27090|TGFB2_MOUSE Transforming growth factor beta-2 proprotein (Gene Name=Tgfb2)

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