Structure of PDB 5twf Chain A

Receptor sequence
>5twfA (length=189) Species: 9606 (Homo sapiens) [Search protein sequence]
PEGSHQYELLKHAEATLGSGNLRQAVMLPEGEDLNEWIAVNTVDFFNQIN
MLYGTITEFCTEASCPVMSAYEYHWADGTNIKKPIKCSAPKYIDYLMTWV
QDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQ
LEEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKL
3D structure
PDB5twf Regulation of Protein Interactions by Mps One Binder (MOB1) Phosphorylation.
ChainA
Resolution3.136 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A C79 H161 H166 C60 H139 H144
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0030295 protein kinase activator activity
GO:0043539 protein serine/threonine kinase activator activity
GO:0046872 metal ion binding
Biological Process
GO:0035329 hippo signaling
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0070062 extracellular exosome

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:5twf, PDBe:5twf, PDBj:5twf
PDBsum5twf
PubMed28373297
UniProtQ9H8S9|MOB1A_HUMAN MOB kinase activator 1A (Gene Name=MOB1A)

[Back to BioLiP]