Structure of PDB 5tw5 Chain A

Receptor sequence
>5tw5A (length=273) Species: 10090 (Mus musculus) [Search protein sequence]
NYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSNDSATISFTKPWSQG
KLSNQQWEKLQHMFQVYRVSFTRDIQELVKMMSPKEDYPIEIQLSAGCEM
YPGNASESFLHVAFQGKYVVRFWGTSWQTVPGAPSWLDLPIKVLNADQGT
SATVQMLLNDTCPLFVRGLLEAGKSDLEKQEKPVAWLSSVPSSAHGHRQL
VCHVSGFYPKPVWVMWMRGDQEQQGTHRGDFLPNADETWYLQATLDVEAG
EEAGLACRVKHSSLGGQDIILYW
3D structure
PDB5tw5 Galactosylsphingamides: new alpha-GalCer analogues to probe the F'-pocket of CD1d.
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 7LM A Y73 S76 D80 F120 W133 W142 L143 L150 D153 T156 Y67 S70 D74 F114 W127 W136 L137 L144 D147 T150 PDBbind-CN: -logKd/Ki=7.42,Kd=38.1nM
External links
PDB RCSB:5tw5, PDBe:5tw5, PDBj:5tw5
PDBsum5tw5
PubMed28655912
UniProtP11609|CD1D1_MOUSE Antigen-presenting glycoprotein CD1d1 (Gene Name=Cd1d1)

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