Structure of PDB 5tw2 Chain A

Receptor sequence
>5tw2A (length=267) Species: 10090 (Mus musculus) [Search protein sequence]
NYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSNDSATISFTKPWSQG
KLSNQQWEKLQHMFQVYRVSFTRDIQELVKMMSPKEDYPIEIQLSAGCEM
YPASESFLHVAFQGKYVVRFWGTSWQTVPGAPSWLDLPIKVLNADQGTSA
TVQMLLNDTCPLFVRGLLEAGKSDLEKQEKPVAWLSSVPGHRQLVCHVSG
FYPKPVWVMWMRGDQEQQGTHRGDFLPNADETWYLQATLDVEAGEEAGLA
CRVKHSSLGGQDIILYW
3D structure
PDB5tw2 Galactosylsphingamides: new alpha-GalCer analogues to probe the F'-pocket of CD1d.
ChainA
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FUC A S114 G130 S106 G122
BS02 7LP A Y73 S76 F77 D80 L84 F120 W133 L150 D153 T156 Y67 S70 F71 D74 L78 F112 W125 L142 D145 T148 PDBbind-CN: -logKd/Ki=7.30,Kd=49.7nM
External links
PDB RCSB:5tw2, PDBe:5tw2, PDBj:5tw2
PDBsum5tw2
PubMed28655912
UniProtP11609|CD1D1_MOUSE Antigen-presenting glycoprotein CD1d1 (Gene Name=Cd1d1)

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